abstract：:SARS-CoV-2 infection is causing a pandemic disease that is reflected in challenging public health problems worldwide. Human leukocyte antigen (HLA)-based epitope prediction and its association with disease outcomes provide an important base for treatment design. A bioinformatic prediction of T cell epitopes and their ...

journal_title：Journal of medical virology

authors： Romero-López JP,Carnalla-Cortés M,Pacheco-Olvera DL,Ocampo-Godínez JM,Oliva-Ramírez J,Moreno-Manjón J,Bernal-Alferes B,López-Olmedo N,García-Latorre E,Domínguez-López ML,Reyes-Sandoval A,Jiménez-Zamudio L

更新日期：2020-09-28 00:00:00

abstract：:Severe hemorrhagic fever disease is caused by severe fever with thrombocytopenia syndrome virus (SFTSV) infection, which belongs to the Phlebovirus genus in the Bunyaviridae family. A comprehensive literature search of PubMed, Web of Science, Embase, Cochrane Library, Chinese National Knowledge Infrastructure database...

journal_title：Journal of medical virology

authors： Wang X,Ren X,Ge Z,Cui S,Wang L,Chen Z,Tian D

更新日期：2020-09-15 00:00:00

abstract：:The recent emergence of coronavirus disease 2019 (COVID-19) pandemic has reassessed the usefulness of historic convalescent plasma transfusion (CPT). This review was conducted to evaluate the effectiveness of CPT therapy in COVID-19 patients based on the publications reported till date. To our knowledge, this is the f...

journal_title：Journal of medical virology

authors： Rajendran K,Krishnasamy N,Rangarajan J,Rathinam J,Natarajan M,Ramachandran A

更新日期：2020-09-01 00:00:00

abstract：:The 2020 coronavirus pandemic is developing at different paces throughout the world. Some areas, like the Caribbean Basin, have yet to see the virus strike at full force. When it does, there is reasonable evidence to suggest the consequent COVID-19 outbreaks will overwhelm healthcare systems and economies. This is par...

journal_title：Journal of medical virology

authors： de Ángel Solá DE,Wang L,Vázquez M,Méndez-Lázaro PA

更新日期：2020-09-01 00:00:00

abstract：:Nutrient starvation is a common phenomenon that occurs during T cell activation. Upon pathogen infection, large amounts of immune cells migrate to infection sites, and antigen-specific T cells are activated; this is followed by rapid proliferation through clonal expansion. The dramatic expansion of cells will commonly...

journal_title：Journal of medical virology

authors： Lu J,Jia J,Zhang J,Liu X

更新日期：2020-08-13 00:00:00

abstract：:Parechoviruses are emerging pathogens of humans often affecting the pediatric age group, with a growing line of evidence implicating them as agents of a broad spectrum of clinical syndromes in adults. However, because many clinicians are not familiar with the manifestation of the infections, they are not included in t...

journal_title：Journal of medical virology

authors： Kabuga AI,Nejati A,Soheili P,Shahmahmoodi S

更新日期：2020-08-06 00:00:00

abstract：INTRODUCTION:Although the effectiveness of direct-acting antivirals (DAAs) for the treatment of chronic hepatitis C virus (HCV) has been reported in real-world settings, predictive factors of treatment failure are lacking. Therefore, we sought to explore the baseline predictors of treatment response to DAAs. METHODS:T...

journal_title：Journal of medical virology

authors： Ridruejo E,Piñero F,Mendizabal M,Cheinquer H,Wolff FH,Anders M,Reggiardo V,Ameigeiras B,Palazzo A,Alonso C,Schinoni MI,Zuain MGV,Tanno F,Figueroa S,Santos L,Peralta M,Soza A,Vistarini C,Adrover R,Fernández N,Perez

更新日期：2020-08-04 00:00:00

abstract：:Hepatitis A incidence has been decreasing in Brazil since child vaccination was implemented in 2014. This trend was interrupted by an outbreak among adult male in São Paulo in 2017. This study was outlined to estimate whether the increase of hepatitis A cases among adult men in Brazil was restricted to São Paulo. Case...

journal_title：Journal of medical virology

authors： De Oliveira TM,Vieira NSG,Sepp TDS,Souto FJD

更新日期：2020-08-01 00:00:00

abstract：:Citrullinated histone H3 (H3Cit) is the product of the conversion of peptidylarginine to citrulline in histone H3. We evaluated the H3Cit level in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) tissues and assessed its association with Beclin1 messenger RNA (mRNA) (a key autophagic regulator). The leve...

journal_title：Journal of medical virology

authors： Lu M,Zhang X,Xu Y,He G,Liu Q,Zhu J,Zhang C

更新日期：2020-08-01 00:00:00

abstract：:Influenza is a public health burden, responsible for more than half a million deaths worldwide each year and explosive outbreaks in-hospital care units. At present, little is known about clinical characteristics and outcomes with nosocomial influenza infection. To assess clinical characteristics and outcome between no...

journal_title：Journal of medical virology

authors： Naudion P,Lepiller Q,Bouiller K

更新日期：2020-08-01 00:00:00

abstract：:Human bocavirus (HBoV) is known to be associated with a variety of clinical manifestation including acute gastroenteritis (AGE). Despite their global prevalence, no data is available on the epidemiology of HBoV associated with AGE in South Africa (SA). Between April 2009 and April 2015, 3765 stool specimens were colle...

journal_title：Journal of medical virology

authors： Netshikweta R,Chidamba L,Nadan S,Taylor MB,Page NA

更新日期：2020-08-01 00:00:00

abstract：PROBLEM:Objective studies that use validated questionnaires are needed to evaluate the changes in the sexual functions of women diagnosed with human papillomavirus (HPV) infection. METHOD OF STUDY:The study comprised 80 sexually active women diagnosed with a high-risk HPV infection. These patients were divided into fo...

journal_title：Journal of medical virology

authors： Alay I,Kaya C,Karaca I,Yildiz S,Baghaki S,Cengiz H,Ekin M,Yasar L

更新日期：2020-08-01 00:00:00

abstract：:There are limited reports on the etiology of multiple enteric viruses causing acute gastroenteritis (AGE) in North India. In the present study we have determined the prevalence of three enteric viruses, namely rotavirus, astrovirus (AstV) and adenovirus (AdV) in a total of 312 diarrheic children (<5 years) hospitalize...

journal_title：Journal of medical virology

authors： Akdag AI,Gupta S,Khan N,Upadhayay A,Ray P

更新日期：2020-08-01 00:00:00

abstract：:Annual outbreaks of seasonal influenza cause a substantial health burden. The aim of this study was to compare patient demographic/clinical data in two influenza patient groups presenting to hospital; those requiring O2 or critical care admission and those requiring less intensive treatment. The study was conducted fr...

journal_title：Journal of medical virology

authors： Dominic C,Welch C,Melzer M

更新日期：2020-07-31 00:00:00

abstract：:The purpose of this study was to determine whether autophagy regulates the expression of human cytomegalovirus (HCMV) immediately early two viral protein (IE2). Rapamycin and 3-methyladenine (3-MA) were used to stimulate or suppress autophagy during HCMV infection. UL122 recombinant plasmid was transfected to overexpr...

journal_title：Journal of medical virology

authors： Zhang X,Xi T,Zhang L,Bi Y,Huang Y,Lu Y,Liu X,Fang F

更新日期：2020-07-25 00:00:00

abstract：:Glycoproteins of enveloped viruses replicating in nonprimate mammalian cells carry α-1,3-galactose (α-Gal) glycans, and can bind to anti-Gal antibodies which are abundant in humans. The antibodies have protected humans and their ancestors for millions of years, because they inhibit replication of many kinds of microbe...

journal_title：Journal of medical virology

authors： Chen JM

更新日期：2020-07-18 00:00:00

abstract：:Distinct human papillomavirus (HPV) 18 variants are thought to differ in oncogenic potential and geographic distribution. As such, understanding the regional variants of HPV 18 would be of great importance for evolutionary, epidemiological, and biological analysis. In this regard, the sequence variations of E6 gene we...

journal_title：Journal of medical virology

authors： Salavatiha Z,Shoja Z,Heydari N,Marashi SM,Younesi S,Nozarian Z,Jalilvand S

更新日期：2020-07-09 00:00:00

abstract：:Data on the serological response toward severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 16 recent reports were analyzed and a high degree of variability was shown. Immunoglobulin M (IgM) responses were either found earlier than IgG, or together with IgG, later than IgG, or were missing. Therefore, clea...

journal_title：Journal of medical virology

authors： Bauer G

更新日期：2020-07-07 00:00:00

abstract：:Coronavirus disease-2019 (COVID-19) infection and its severity can be explained by the concentration of glycosylated severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) viral particles in the lung epithelium, the concentration of glycosylated angiotensin-converting enzyme receptor 2 (ACE2) in the lung epithel...

journal_title：Journal of medical virology

authors： Brufsky A

更新日期：2020-07-01 00:00:00

abstract：:Neurologic sequelae can be devastating complications of respiratory viral infections. We report the presence of virus in neural and capillary endothelial cells in frontal lobe tissue obtained at postmortem examination from a patient infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Our observ...

journal_title：Journal of medical virology

authors： Paniz-Mondolfi A,Bryce C,Grimes Z,Gordon RE,Reidy J,Lednicky J,Sordillo EM,Fowkes M

更新日期：2020-07-01 00:00:00

abstract：:With multiple virus epicenters, COVID-19 has been declared a pandemic by the World Health Organization. Consequently, many countries have implemented different policies to manage this crisis including curfew and lockdown. However, the efficacy of individual policies remains unclear with respect to COVID-19 case develo...

journal_title：Journal of medical virology

authors： Khosrawipour V,Lau H,Khosrawipour T,Kocbach P,Ichii H,Bania J,Mikolajczyk A

更新日期：2020-07-01 00:00:00

abstract：:In mid-December 2019, a disease caused by infection with severe acute respiratory syndrome coronavirus-2, which began in Wuhan, China, has spread throughout the country and many countries around the world. The number of children with coronavirus disease-2019 (COVID-19) has also increased significantly. Although inform...

journal_title：Journal of medical virology

authors： She J,Liu L,Liu W

更新日期：2020-07-01 00:00:00

abstract：:COVID-19 pandemic has affected over 100 countries in a matter of weeks. People's response toward social distancing in the emerging pandemic is uncertain. In this study, we evaluated the influence of information (formal and informal) sources on situational awareness of the public for adopting health-protective behavior...

journal_title：Journal of medical virology

authors： Qazi A,Qazi J,Naseer K,Zeeshan M,Hardaker G,Maitama JZ,Haruna K

更新日期：2020-07-01 00:00:00

abstract：:In the ongoing coronavirus disease 2019 (COVID-19) pandemic, one potential cause of concern is that some discharged COVID-19 patients are testing positive again for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA. To better understand what is happening and to provide public health policy planners and ...

journal_title：Journal of medical virology

authors： Han Z,Battaglia F,Terlecky SR

更新日期：2020-07-01 00:00:00

abstract：:Hepatitis B virus (HBV) genotypes impact treatment outcomes and disease progression. The current genotyping methods have limitations in patients with low HBV viral load. In this study, a more sensitive assay has been developed for determining the HBV genotype in HBV DNA suppressed patients. Fifty-five serum samples fr...

journal_title：Journal of medical virology

authors： Liu Y,May L,Liu X,Martin R,Svarovskaia E,Gaggar A,Mo H,Feierbach B

更新日期：2020-07-01 00:00:00

abstract：:The rapid spread of the epidemic has aroused widespread concern in the international community. Severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) was first reported in China, with bats as the likely original hosts and pangolins as potential intermediate hosts. The current source of the disease is mainly pat...

journal_title：Journal of medical virology

authors： Ye Q,Wang B,Mao J,Fu J,Shang S,Shu Q,Zhang T

更新日期：2020-07-01 00:00:00

abstract：:Palatine tonsils have been observed to harbor several distinct respiratory and herpesviruses in separate studies. In this study, the presence of these viruses in palatine tonsils was comprehensively studied in both children and adults. A cross-sectional analysis of 181 patients (median age 22 years; range, 2.6-66) ope...

journal_title：Journal of medical virology

authors： Silvoniemi A,Mikola E,Ivaska L,Jeskanen M,Löyttyniemi E,Puhakka T,Vuorinen T,Jartti T

更新日期：2020-06-30 00:00:00

abstract：:Hepatitis E virus (HEV) infection is considered a neglected disease of major concern in developed countries. Clinically, HEV occurs as an acute and self-limited disease, though chronic cases mostly associated to HEV-3 are now being commonly reported in immunocompromised individuals and solid organ transplant recipient...

journal_title：Journal of medical virology

authors： Bangueses F,Abin-Carriquiry JA,Cancela F,Curbelo J,Mirazo S

更新日期：2020-06-27 00:00:00

abstract：:This study aimed to investigate the prevalence trend of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections and their genotype distribution among hemodialysis patients, determining their long-term prognosis and the risk factors to the mortality. This cohort study used both the medical data and the blood sam...

journal_title：Journal of medical virology

authors： Ko K,Nagashima S,Yamamoto C,Takahashi K,Matsuo J,Ohisa M,Akita T,Matyakubov J,Mirzaev U,Katayama K,Masaki T,Tanaka J

更新日期：2020-06-24 00:00:00

abstract：:Human cytomegalovirus (HCMV) is the leading cause of congenital infection and an opportunistic pathogen capable of establishing lifelong latency. In the present study, we aimed to investigate the distribution of glycoprotein B, H, and N in infants of Shanghai and correlate the genotype with active and latent HCMV infe...

journal_title：Journal of medical virology

authors： Dong N,Cao L,Su L,Lu L,Dong Z,Xu M,Xu J

更新日期：2020-06-21 00:00:00

abstract：:The current study aimed to investigate the diagnostic value of glycated albumin (GA), glycated hemoglobin (HbA1c), and a number of routine biomarkers as noninvasive indicators of liver fibrosis in patients with chronic hepatitis C (CHC). One hundred patients with CHC were subjected to full medical history and examinat...

journal_title：Journal of medical virology

authors： Abo El-Khair SM,El-Alfy HA,Elsamanoudy AZ,Elhammady D,Abd-Elfattah N,Eldeek B,Farid K

更新日期：2020-06-19 00:00:00

abstract：:Starting around December 2019, an epidemic of pneumonia, which was named COVID-19 by the World Health Organization, broke out in Wuhan, China, and is spreading throughout the world. A new coronavirus, named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by the Coronavirus Study Group of the International...

journal_title：Journal of medical virology

authors： Wang C,Liu Z,Chen Z,Huang X,Xu M,He T,Zhang Z

更新日期：2020-06-01 00:00:00

abstract：:There is an obvious concern globally regarding the fact about the emerging coronavirus 2019 novel coronavirus (2019-nCoV) as a worldwide public health threat. As the outbreak of COVID-19 causes by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) progresses within China and beyond, rapidly available epi...

journal_title：Journal of medical virology

authors： Dey SK,Rahman MM,Siddiqi UR,Howlader A

更新日期：2020-06-01 00:00:00

abstract：:Acute gastroenteritis (AGE) is a common illness in both adults and children worldwide and is caused by several microorganisms including viruses, bacteria, and parasites. Rotavirus (RV), which is the main cause of AGE, can occur as a mixed infection with other viruses. The aim of this study is to assess the molecular e...

journal_title：Journal of medical virology

authors： Gibory M,Dembinski JL,Flem E,Haltbakk I,Dudman SG

更新日期：2020-05-15 00:00:00

abstract：:Sex differences in the predictors for hepatocellular carcinoma (HCC) development after direct-acting antiviral (DAA) therapy was investigated. DAA therapy was given to 1438 (663 male, 775 female) patients. Sex differences in the HCC development rate and the factors contributing to HCC development after DAA therapy wer...

journal_title：Journal of medical virology

authors： Watanabe T,Tokumoto Y,Joko K,Michitaka K,Horiike N,Tanaka Y,Tada F,Kisaka Y,Nakanishi S,Yamauchi K,Yukimoto A,Nakamura Y,Hirooka M,Abe M,Hiasa Y

更新日期：2020-05-06 00:00:00

abstract：:Epstein-Barr virus (EBV) DNA load in the blood increases in posttransplant lymphoproliferative disorders and chronic active EBV infection. In this report, we analyzed the EBV DNA load in the peripheral blood mononuclear cells (PBMCs) and plasma of patients with hydroa vacciniforme (HV) and/or hypersensitivity to mosqu...

journal_title：Journal of medical virology

authors： Miyake T,Iwatsuki K,Hirai Y,Yamamoto T,Hamada T,Fujii K,Imamura H,Morizane S

更新日期：2020-04-07 00:00:00

abstract：:To investigate the genetic diversity, time origin, and evolutionary history of the 2019-nCoV outbreak in China and Thailand, a total of 12 genome sequences of the virus with known sampling date (24 December 2019 and 13 January 2020) and geographic location (primarily Wuhan city, Hubei Province, China, but also Bangkok...

journal_title：Journal of medical virology

authors： Li X,Zai J,Wang X,Li Y

更新日期：2020-04-01 00:00:00

abstract：:Antigenic drift of the hemagglutinin (HA) and neuraminidase (NA) proteins of the influenza virus cause a decrease in vaccine efficacy. Since the information about the evolution of these viruses in Saudi is deficient so we investigated the genetic diversity of circulating H1N1 viruses. Nasopharyngeal aspirates/swabs co...

journal_title：Journal of medical virology

authors： Naeem A,Elbakkouri K,Alfaiz A,Hamed ME,Alsaran H,AlOtaiby S,Enani M,Alosaimi B

更新日期：2020-03-11 00:00:00

abstract：:Poliovirus (PV) is a member of the species Enterovirus C (EV-C), which may cause irreversible paralysis and death. So, for the purpose of analyzing the evolution of PV2 to help in eradicating PVs globally, a recombination analysis was performed to verify all viral genomes of EV-C, and we found 13 putative recombinatio...

journal_title：Journal of medical virology

authors： Qian Y,Pu X,Yu Y,Yu X,Kong L,Liu L,Wang H,Shen H

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Recent influenza B/Victoria lineage viruses contain amino acid deletions at positions 162 to 164 of the haemagglutinin (HA) protein. These amino acid deletions have affected the detection of B/Victoria lineage viruses by the lineage-specific conventional reverse-transcription polymerase chain reaction (RT-PC...

journal_title：Journal of medical virology

authors： Chan WM,Wong LH,So CF,Chen LL,Wu WL,Ip JD,Lam AH,Yip CCY,Yuen KY,To KKW

更新日期：2020-03-01 00:00:00